When a parent finds out that their child has head lice the first thing they want to know is what kills lice? As a responsible parent you need to know that only poisonous pesticides will actually kill lice. The problem with using them is that the poison you are applying to your child's head is also dangerous for your child. Licenders natural head lice shampoo is made with enzymes which break the shell of the louse. This makes it easier to comb out the lice and get rid of LICE.